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RT @ArditiMd: @soundgmh @BrodinPetter @yoncabulutmd @LaelYonker @LeviHoste @VirusesImmunity @CastlTrAstonDrs @DrKenRemy1 Sure.There are man…
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@soundgmh @BrodinPetter @yoncabulutmd @LaelYonker @LeviHoste @VirusesImmunity @CastlTrAstonDrs @DrKenRemy1 Sure.There are many shared immune responses to viral infections & autoimmune diseases.The Key common signaling mol is IL1 b in both of these infl
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From August: "We identify a highly inflammatory MIS-C subset of patients that show both enhanced neutrophil activation & imprints of harmful adaptive immune responses...." #COVID19 https://t.co/RrqdXqHdhZ https://t.co/GMl1GluGFu
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@ChristophKessel @MDPatT2 @AllergyEaaci @LorenzThurner Yes many papers showing autoabs in #MISC ex: https://t.co/ewex33YyRJ , https://t.co/hyh3IdU3yz & https://t.co/133B3sivxJ and in #COVID19, ex: https://t.co/8Ea6wCRtzX and many more…
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A: anche perché il coinvolgimento epatico (per esempio nella MIS-C) non corrisponde mai a un pannello autoimmunne classico di tipo epatico. Le "signature" autoimmuni sono di altra natura https://t.co/gOo9fkGx7v 16/16
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@villagerssn @KathMLee1 @Paul_Bogdanich Here are some of the papers that point to many of these things . The fact is that the jabs are basically autoimmunity and hyper inflammation in a vial. https://t.co/iBNq6iEBnb https://t.co/T8davroSLZ https://t.co/nG
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…
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RT @BagaiDr: Autoimmune signat:hyperinflam.MIS-C:severe,⬆️inflam,multiorgan-wks post SARSCoV2;proteomic,RNA seq,autoAbs,Bcell R(BCR)reperto…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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... autoantibodies against immunomodulatory mediators and antigens from endothelial, cardiac, and GI tissues have been identified and may play a role in driving MIS-C pathogenesis." https://t.co/8DByNb8WMM
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RT @jclinicalinvest: The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children: https://t.co/JSNHGDhjaB @…
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RT @jclinicalinvest: The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children: https://t.co/JSNHGDhjaB @…
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RT @jclinicalinvest: The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children: https://t.co/JSNHGDhjaB @…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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Great paper by @ArditiMd! It’s very exciting to see clearly autoreactive BCR characteristics such as IGHV 4-34 in MIS-C group.
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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Much of this information is beyond my scope of knowledge and understanding, but always grateful for the dedicated work of researchers who endeavour to figure these things out.
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RT @VSLanziotti: Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signature…
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Outstanding paper @jclinicalinvest by @ArditiMd et al aimed to characterize/identify pathogenic pathways, ptns & signatures assoc w/ #MISC by 🔹proteomics 🔹RNA-seq 🔹autoantibody arrays & BCR-seq 🔹analysed samples of mild & severe MIS-C,KD,health
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RT @jclinicalinvest: The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children: https://t.co/JSNHGDhjaB @…
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RT @BagaiDr: Autoimmune signat:hyperinflam.MIS-C:severe,⬆️inflam,multiorgan-wks post SARSCoV2;proteomic,RNA seq,autoAbs,Bcell R(BCR)reperto…
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2)MIS-C:cluster link-TRBV11-2 expand(TCR)repertoire,superAg;combin patho path;⬆️CRP,ferritin,D-dimer,cytokine;ICU 58%;innate-adaptive;⬆️activ myeloid cell,Neutro/Monocy chemotaxis,Tcell lymphopenia,⬆️Tcell activ,⬆️vascular patrol CX3CR1+CD8+Tcell;HLA class
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Autoimmune signat:hyperinflam.MIS-C:severe,⬆️inflam,multiorgan-wks post SARSCoV2;proteomic,RNA seq,autoAbs,Bcell R(BCR)repertoire,immunopatho,Inflam marker,humoral,Neutro activ,complement- coagul path;⬆️severe,auto-Super Ag;anti-S IgG,autoAbs;Ig(IGHV)gene
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children: https://t.co/JSNHGDhjaB @ArditiMd @CedarsSinai #COVID_19 #Inflammation
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RT @unimedhal: Die beiden Paper sind unter folgenden Links abrufbar (#FreeAccess): https://t.co/sAryFOhHgP und https://t.co/Gb8H2BJb6A
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Die beiden Paper sind unter folgenden Links abrufbar (#FreeAccess): https://t.co/sAryFOhHgP und https://t.co/Gb8H2BJb6A
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We thank many of our amazing collaborators without them this could not have been published. Thank you. “It takes a village” to do these studies.
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Another paper out by Rebecca Porritt and others in our lab and several fantastic collaborators on #MISC and autoimmune signatures by multiomics immune phenotyping. Our JCI paper now fully published. https://t.co/fN2dFHVmsz
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ומה הלאה? הגוף מתחיל לייצר נוגדנים כנגד התאים שלו. הם הצליחו להראות את זה בכמה שיטות, יש נזק לרקמות שונות https://t.co/gWdYVqtKi3 הם גם הראו בפרסום מאוחר יותר שיש נטיה גנטית של חלבוני MHC-I לMIS-C חמור: https://t.co/7mfy7iKWD5 (6/8) https://t.co/PkUJLjth9B
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Ett paper till som identifierar TRBV11-2-receptorn som problematisk vid MIS-C efter covid. https://t.co/1aeZgzi1b2 https://t.co/mvv9Vs03iX
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/JGeCc0EAs0 #science #genomics
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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RT @ArditiMd: The summary of our papers in MISC so far: 1-it is associated wTCR VB11-2 skewing (suggestive of SAg resp) 2- combination of H…
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RT @ArditiMd: The summary of our papers in MISC so far: 1-it is associated wTCR VB11-2 skewing (suggestive of SAg resp) 2- combination of H…
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RT @ArditiMd: The summary of our papers in MISC so far: 1-it is associated wTCR VB11-2 skewing (suggestive of SAg resp) 2- combination of H…
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RT @ArditiMd: The summary of our papers in MISC so far: 1-it is associated wTCR VB11-2 skewing (suggestive of SAg resp) 2- combination of H…
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The summary of our papers in MISC so far: 1-it is associated wTCR VB11-2 skewing (suggestive of SAg resp) 2- combination of HLA A*02, B*35, C*04 alleles suggesting genetic suscep. 3-autoimmune signature and BCR responses similar to autoimmune,4: >gut p
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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RT @yoncabulutmd: Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper b…
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Clinical laboratory and cytokine profiles of mild and severe #MISC patients Supplemental data from the original paper by @ArditiMd explains why Anakinra, Infliximab would work #Covid19 #PEdsICU #autoantibody https://t.co/qQwyVyp6Zq https://t.co/JLuVDz2
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This fits perfectly with our most recent findings of “autoimmune signature” in MISC kids and the key role of IL1 b in pathogenesis. https://t.co/2TqNrIQbd9
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/JGeCc0EAs0 #science #genomics
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/UJkxfH0aUT #science #genomics
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/JGeCc0EAs0 #science #genomics
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JCI - The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/gRoNb97i64
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@jerrys237 @LeviHoste @FReichert667 @lizWWyld @apsmunro @Damian_Roland Thank you. It was followed by this very recently in Press. https://t.co/K4R3oavED5
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RT @ArditiMd: 👍 Nice Review. since acceptance of this Review in May, Several new key papers came out on MISC being an autoimmune disease…
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RT @ArditiMd: 👍 Nice Review. since acceptance of this Review in May, Several new key papers came out on MISC being an autoimmune disease…
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👍 Nice Review. since acceptance of this Review in May, Several new key papers came out on MISC being an autoimmune disease likely after prolinged and repeated exposures to Spike S1 ( Superantigen motif). https://t.co/K4R3oavED5
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RT @genomeorganizer: The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/JGeCc0EAs0 #s…
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/JGeCc0EAs0 #science #genomics
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The autoimmune signature of hyperinflammatory MIS-C https://t.co/0quBNkCMgK https://t.co/iI3p979YeO "This cluster was linked to a TRBV11-2 expanded T cell receptor (TCR) repertoire, consistent with previous studies indicating a superantigen-driven patho
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MIS-C (#MISC), a rare but serious inflammatory condition that affects children who contract #COVID19, produces a distinctive pattern of biomarkers that may help physicians predict disease severity and also aid researchers in developing new treatments. http
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/JGeCc0EAs0 #science #genomics
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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RT @Primary_Immune: Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformati…
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Intriguing new clues into the pathogenesis of #COVID19-associated "MIS-C" _News: https://t.co/FOMyKAJXSE #bioinformatics #bigdata #snrtg #openscience #meded #scicomm _Journal: https://t.co/MtloEZwvWy #autoimmune #MISC #immunology #genomics https://t.co/I
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JCI - The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children https://t.co/XMLG7y01ON
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…
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Yes Another Fantastic collaboration with @lab_binder on MIS-C. https://t.co/K4R3oavED5
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RT @ArditiMd: Great collaborative @jclinicalinvest manuscript on MIS-C from @CedarsSinai https://t.co/yB6IkhefAh
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…
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RT @yoncabulutmd: More answers to #MISC #PIMSTS Multisystem Inflammatory Syndrome in Children #covid19 Strong autoimmune signatures #super…